Tag: trigriluzole
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Why I’m Skeptical of Troriluzole for SCA3
I’m skeptical of a 20-plus-year-old drug (riluzole)—shown mostly ineffective for SCA3 (and SCA2)—in a new prodrug package (named BHV-4157 in 2016; also called trigriluzole in 2017; renamed to troriluzole in 2018) being then on-label repurposed for SCA/SCA3. This seems to me to be primarily a money-generating move, and yes, I do accept that, because I accept…
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What is BHV-4157?
2018-08-14. Trigriluzole was renamed to troriluzole. On 2018-11-02, most references to trigriluzole and BHV-4157 were removed from the Biohaven website. 2017-October: After SCA trials failed, Biohaven was quick to remove some SCA-related information from their website (hence, some broken URLs). See here. Later, they resumed testing after doubling the dose. 2017-April (or so): Biohaven removed…