Tag: drug repurposing

  • Citalopram and SCA3

    Most technical papers on SCA are more advanced than I can comprehend. Every sentence can be chock-full of references that I don’t fully understand. This article takes an example of what looks like a promising SCA3 study involving drug repurposing and dissects it. Here’s the study, published 2015-09-15: https://www.researchgate.net/publication/282042707_Serotonergic_signalling_suppresses_ataxin_3_aggregation_and_neurotoxicity_in_animal_models_of_Machado-Joseph_disease Breaking down the summary Here’s a…

  • Drug Repurposing

    This is an outsider’s view of what drug repurposing is about. When a drug is approved by the FDA, it is approved for a specific purpose. When an FDA-approved drug is used safely for a purpose other than for what it was approved, that is referred to as using it off-label. If a drug is…